PATfix Process Analytical Technology

Our PATfix analytical HPLC is the ideal system for routine gradient separations that enables you to do every analytical task.

  • High pressure gradient pump
  • Pump head flow rates up to 10mL/min
  • Highly sensitive multi-wavelength detector

Data and System Management

Along with a preconfigured chromatographic system characterization, our PATFix allows you to test your chromatographic system based on best-practices within the industry.


Quantification of Key Process Parameters

Our PATFix system can follow impurity, product formation, and clearance in upstream and downstream processes, featuring simple to use multivariate and univariate model building tools that are tailored for chromatographic data.


Features & Benefits

  • High pressure gradient pump (up to 400 bar) with integrated degasser and mixer
  • Bio-buffer compatible ceramic pump heads allowing flow rates of up to 10 mL/min also suitable for semi preparative HPLC
  • Highly sensitive multi-wavelength detector with intelligent temperature control to minimize signal drift
  • Fluorescence detector
  • Temperature controlled autosampler for maximal working efficiency
  • Extensive safety features such as leak management sensor


  • Raw material control: Production of Intravenous IgG from Cohn I+II+III paste
  • Adenovirus purification
  • Monitoring of impurity formation in recombinant upstream processes
  • Raw material quality evaluation
  • As well as many other applications

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