PATfix Process Analytical Technology
Data and System Management
Along with a preconfigured chromatographic system characterization, our PATFix allows you to test your chromatographic system based on best-practices within the industry.
Quantification of Key Process Parameters
Our PATFix system can follow impurity, product formation, and clearance in upstream and downstream processes, featuring simple to use multivariate and univariate model building tools that are tailored for chromatographic data.
Overview
Efficient Process Analytical Technology requires fast and robust analytical techniques which enables you to assess high quality information about critical quality attributes and key performance indicators as parallel as possible to the manufacturing process. This is where BIA Separations’ PATfix Analytical HPLC system comes in.
Our BIA Separation’s PATfix analytical HPLC system aims to enhance bioprocess understanding and implies a holistic approach to ensure that quality is built into products by design. This system is equipped with bio-inert ceramic heads and is deliberately tailored to meet the demands of analytical applications covering a wide range of biomolecules. It is highly sensitive and a fast, multi-wave length detector enabling detection of component peaks even in very fast gradients.
Features & Benefits
- High pressure gradient pump (up to 400 bar) with integrated degasser and mixer
- Bio-buffer compatible ceramic pump heads allowing flow rates of up to 10 mL/min also suitable for semi preparative HPLC
- Highly sensitive multi-wavelength detector with intelligent temperature control to minimize signal drift
- Fluorescence detector
- Temperature controlled autosampler for maximal working efficiency
- Extensive safety features such as leak management sensor
Documents
Applications
- Raw material control: Production of Intravenous IgG from Cohn I+II+III paste
- Adenovirus purification
- Monitoring of impurity formation in recombinant upstream processes
- Raw material quality evaluation
- As well as many other applications
Related Products
Preparative Monolithic Chromatography Columns
Pre-packed monolithic chromatography columns that eliminate packing, unpacking and repacking from your downstream purification process.
Analytical Chromatography Columns
Our columns combine all characteristics of CIM monoliths on an analytical scale and are ideal for process analytical technology (PAT).
