How to Choose the Right Bioreactor System for You
Not sure where to start with our Bioreactor System catalog? Use our comprehensive guide to find which solution is the best fit for you and your process.
What is a Bioreactor?
A bioreactor is a vessel, device, or system that provides a tightly controlled environment in order to culture cells or microorganisms. They are typically used during the upstream bioprocessing portion of the bioprocess. In order to understand the technical aspects of upstream bioprocessing, as well as the role bioreactor systems play in it, visit our article “What is Upstream Bioprocessing?”.
In the article below, we take a look at the unique features of the bioreactor systems to help you discover which is the best solution for your needs.
SUPR Single-Use bioReactor
Designed to simplify your bioprocess and speed up development, our SUPR bioReactor features closed processing and click-n-go bag loading. It has applications across cell & gene therapies, diagnostics, monoclonal antibodies (mAbs), and vaccines. With all bioreactor materials being fully qualified for biological product contact, the SUPR eliminates cross-contamination risks. Additionally, no sterilization or cleaning validations are required, as the SUPR comes gamma irradiated.
The SUPR provides a single-use alternative at pilot and production scale to stainless steel bioreactors, allowing for cultivation to continue from research to production. It is composed of four core components: the SUPR cell cultivation center, SUPR holder, temperature control unit, and controller.
SUPR is the Right Bioreactor System for You if You…
- Wish to streamline & simplify your bioreactor process
- Would like to reduce the risk of cross-contamination
- Are using a bioreactor system for cell & gene therapy, diagnostics, mAbs, and vaccine applications
- Would like to increase speed in development
- Want a bioreactor made designed using over five decades of bioprocessing experience
- Need a bioreactor supporting 50L and 250L container volumes
AppliFlex ST
For scalable and reproducible processing at your fingertips, the AppliFlex ST Single-Use Bioreactor features a range of sparger types. Through the use of innovative 3D printing technology, our team of experts can customize your bioreactor by adapting it to your specific process and application. AppliFlex ST eliminates the need for cleaning, preparing, and sterilizing. Thanks to its easier operation and set up, the single-use bioreactor can help you perform experiments in a shorter time, as well as allowing for higher throughput.
The customizability of the AppliFlex ST means that custom tubing kits can be mounted on the headplate, creating the perfect prefabricated bioreactor out of the box. Overall, the 3D printing manufacturing process of the bioreactor means that if you can describe it, we can manufacture it. Contact our expert team at info@hp-ne.com to learn more about customization options.
AppliFlex ST is the Right Bioreactor System for you if you…
- Have a unique process that requires a custom solution
- Would like to improve the reproducibility of your process
- Require a 500mL, 3L, or 15L bioreactor
- Need to add custom tubing kits to your bioreactor system
- Want to increase product yield by reducing operation and setup time
- Need a bioreactor for cell line development, scale up studies, or process development applications such as:
- Cell culture applications
- Cell & gene therapy
- Batch, fed-batch and perfusion
- Fermentations
- And more
Livit Flex Bioprocess Controller
Easily configurable to your research & development applications, whether multi-use or single-use, our Livit Flex Bioprocess Controller was carefully crafted with over forty years of bioprocess control experience. It can be configured as a dual or single control system. The built-in Livit software platform is intuitive and user-friendly.
Livit Flex can accommodate up to 8 mass flow meters, 8 variable speed pumps, or 12 mass flow controllers. It has built-in alarm and user management, and data acquisition. Additionally, the bioprocess controller is OPC-UA compliant, and compatible with Lucullus and V-Control software. It enables plug-and-play connection of auxiliaries and sensors. The controller also automatically recognizes new devices.
Livit Flex is the Right Bioreactor System for you if you…
- Are looking to accelerate your research & development processes
- Would like to set-up & observe experiments from one location
- Require plug-and-play connection of sensors
- Need an easily configurable bioprocess controller
- Require easy-to-use, fully configurable software
- Are utilizing the bioprocess controller for applications in batch cultures, perfusion cultures, cell cultures, microbial cultures, advanced therapy medicinal products (ATMP), continuous cultures, and fed-batch cultures
CellScrew® Adherent Cell Expansion System
Our CellScrew® Adherent Cell Expansion System from Green Elephant Biotech is ideal for reducing manufacturing costs, environmental impact, and time to market. Manufactured with plant-based PLA bioplastic, CellScrew® reduces plastic waste by 90%. In order to create optimal adherent cell attachment conditions, CellScrew® combines an Archimedean Screw, concentric cylinders, and a central tube for a highly oxygenated and continuously mixed environment.
It follows the three-step process of inoculation, incubation, and harvest. Additionally, the system can easily be automated with little outside equipment, and its cell culture area can range from 6,000-10,000cm2. CellScrew® boasts a high surface area to volume ratio, easy handling, and a compact design.
CellScrew® is the Right Bioreactor System for you if you…
- Prioritize sustainability in your process
- Need a high cell culture area in compact housing
- Want to automate your Adherent Cell Expansion process
- Are ready to get your products to market faster
- Need to save incubator space within your process
- Are pursuing application within drug screening & development and vaccine manufacturing
Still Not Sure Which Bioreactor System is Right for You?
Our team of experts would love to set up a call to learn more about your unique needs in order to determine the perfect bioreactor system for you. Reach out to our team at info@hp-ne.com, or get in touch through the form on our contact us page.
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About HPNE
As the industry needs grow, High Purity New England, Inc. continues to supply the biopharmaceutical industry with a range of innovative products, from drug discovery and development to fill-finish, including their flagship product, custom single-use assemblies, as well as pumps, sensors, bioreactor systems, storage and handling solutions and other single-use solutions. Along with their own manufactured products for the global market, they are also a distributor for more than 18 brands in North America.
