Quattroflow 4400 Quaternary
Diaphragm Pump

Our Quattroflow 4400 Single-Use and Multi-Use Pumps feature a high turn-down ratio and compact design.

  • Flow rate of 0.83 – 83 lpm
  • Wide range of flow rates
  • High accuracy in controlling flow rates

Application Note for the QF4400

A test performed on our Quattroflow 4400 Quaternary Diaphragm pump showed that the pressure pulsation measurements were in the range between 0.05 and 0.13 bars.

Minimal Particle Generation

The QF4400 has no mechanical shafts, seals, or wetted rotating parts, helping to minimize particle generation and maintain total product containment without abrasion.


Frequently used in mid-size crossflow systems and chromatography, the Quattroflow 4400 Single-Use and Multi-Use pumps offer a high 100:1 turn-down ratio, which is often a necessity for biopharmaceutical processes. Featuring four pistons, the design of this quaternary diaphragm pump allows for gentle, safe, and secure conveyance of aqueous solutions and biological products that are sensitive to shear force.

The Quattroflow 4400 pump possesses a flow rate of up to 83 lpm at 0 PSI. With its innovative design, this model can be utilized in research, pilot plants, or production facilities throughout the biopharma industry.

Flow rates: 0.83 - 83 lpm
Turndown ratio: 100:1
Single-use configuration: Single-use pump chambers can be supplied gamma irradiated or autoclaved
Multi-use configuration: Stainless steel pump chambers compatible with autoclave, clean-in-place (CIP), and sterilize-in-place (SIP) protocols

Features & Benefits


  • Two different pump chambers available:
    • Multi-use stainless steel
    • Single-use solid polypropylene
  • Extended turndown ratio
  • Flow range of 0.83 - 83 lpm at 0 PSI
  • “All-in-One” technology – integration of pump chamber, pump drive, motor, and integrated controller box
  • Compact design
  • Clean-In-Place (CIP), Steam-In-Place (SIP), and Autoclavable
  • Autoclavability or gamma for single-use models


  • Filtration technology: To recirculate feed/retentate (e.g. membrane cassettes, hollow fibre, spiral wound, ceramic elements)
  • Chromatography: Packing of chromatography columns
  • Feed pump for centrifuges or separators, filling machines, or filter cartridges or plate and frame depth filters
  • As well as many other applications

Technical Specs

Flow Rate Min: Eccentric Shaft 6° 5,000 lph (83 lpm)
Flow Rate Max: Eccentric Shaft 6° 50 lph (0.83 lpm)
Volume Specifications: Approximated Volume per Revolution at Free Output 95 ml
Filling Volume Without Connectors 820 ml
Certificates/ Proofs (Optional): Elastomer (product wetted) USP <88> Cl. VI;FDA21CFR177;BSE/TSE Safe
Stainless Steel Parts (product wetted) 3.1; Surface Roughness; Ferrite Content
Motor Voltage 400 V

Product Comparison

Quattroflow 4400 Diaphragm Pump

Quattroflow 4400
Diaphragm Pump

  • Flow rate: 0.83 - 83 lpm
  • Range of flow rates
  • High accuracy
  • Compact design
  • “All-in-One” technology
  • Extended turndown ratio
FlowMaxx Pro 2500 Quaternary Diaphragm Pump

FlowMaxx Pro 4400
Diaphragm Pump

  • Flow sensor integration
  • Pressure sensor integration
  • Self-priming design
  • Low shear
  • Low heat generation
  • Low cell damage
Quattroflow 2500HT Quaternary Diaphragm Pump

Quattroflow 2500HT
Diaphragm Pump

  • Flow rate: 0.83 - 42 lpm
  • Dry-running
  • Low pulsation
  • Minimal particle generation
  • Low shear
  • All-In-One Technology

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