ReUse HF Cartridges

Our mini-BioProducer ReUse crossflow hollow fiber cartridges are the perfect tool for process development.

  • Gentle processing of cells, biomolecules and viruses
  • Low hold up volume
  • Robust, strong, multi-use hollow fiber membranes

Easy Scale Up/Scale Down

The mini-BioProducer™ ReUse cartridges are offered with the same path length as other high performance WaterSep hollow fiber cartridges, which makes scale up/scale down easy and predictable.

Ideal for Concentration and Diafiltration

These cartridges are ideal for concentration and diafiltration of peptides, enzymes, monoclonal antibodies and other proteins and vaccines as well as cell harvest and cell clarification.

Overview

The mini-BioProducer ReUse cartridges offer a high flux, low binding, hollow fiber cartridge product that can be used repeatedly in upstream and downstream applications and processes. These cartridges integrate WaterSep’s well accepted antifouling, low binding, modified polyethersulfone membrane (m-PES) and are offered in molecular weight cut-offs (MWCO) that range from 3K to 750K and in pore sizes from 0.1µm and 0.65µm, with Lumen ID’s of 0.5 mm, 1.0 mm and 2.0 mm. The antifouling properties of the m-PES membranes typically provide superior process flux and higher product recovery than do most other cross flow devices.

Features & Benefits

  • Self-containment – no assembly – ease of use
  • Gentle processing of cells, biomolecules and viruses
  • Low hold-up volume
  • High process flux, due to antifouling low binding m-PES membrane chemistry
  • Robust, strong, multi-use hollow fiber membranes
  • High yields and easy cleaning
  • 100% integrity tested and ready to use cassettes
  • Very tight specifications and high lot-to-lot membrane consistency
  • Easy and reliable scale up and scale down
  • Very cost effective in large scale format (hollow fiber products that are 4x-6x less expensive than most cassettes and do not require any expensive hardware for installation)

Applications

  • Clarification of cell cultures and fermentation suspensions in primary recovery applications
  • Cell-harvest. Excellent results have been achieved with both E. coli whole cells and E. coli lysates, as well as other microbial process streams
  • Concentration and purification of vaccines
  • Concentration and diafiltration of gene therapy products
  • Concentration/diafiltration of monoclonal antibodies, recombinant proteins, biological macromolecules and peptides
  • As well as many other applications

Product Comparison

BioProducer-660X452

ReUse HP Cartridges

  • Self-containment
  • No assembly
  • Ease of use
  • Low hold-up volume
  • High process flux
  • High yields and easy cleaning
Steamer-660X452

Steamer Line HF Cartridges

  • Gamma irradiated
  • Ready to use
  • No pre-rinse required
  • Humectant free
  • Reduced risk of contamination
  • Consistent, membrane performance
660x452_53872531-25-min

Green Line HF Cartridges

  • No expensive hardware
  • No membrane installation
  • Ready to use
  • No humectants
  • Reduced risk of contamination
  • Consistent, membrane performance

Related Products