Green Line HF
Single-Use Cartridges

The WaterSep mini-BioProducer Green Line HP Single-Use cartridges are gamma irradiated, hollow fiber cartridges available in single cartridge configurations.

  • Gamma irradiated and ready to use
  • Reduced risk of cross contamination
  • Consistent membrane performance batch to batch

Easy Scale Up/Scale Down

These hollow fiber cartridges are offered with the same path length as other high performance WaterSep HF cartridges, which makes scale up and scale down easy and predictable.

For Production Scale Applications

The mini-BioProducer Green hollow fiber cartridges are designed for production scale applications and are the perfect tools for process development.

Overview

The mini-BioProducer Green hollow fiber cartridges are gamma irradiated and ready to use, and utilize WaterSep’s antifouling, low binding, modified polyether sulfone membrane (m-PES) which provides a process flux and product recovery that typically exceeds other crossflow devices. These cartridges are also offered as part of fully integrated open architecture single use crossflow assemblies available with pressure sensors, flow meters, pump heads, aseptic connectors or bags.

Features & Benefits

  • Significant cost savings over traditional cassette formats
  • Gamma irradiated - ready to use - no pre-rinse required
  • No humectants - 80x less extractables, see Extractables Flush Analysis
  • No need for time-consuming cleaning validation
  • Reduced risk of cross contamination
  • Consistent membrane performance batch to batch
  • Self-contained – no assembly – no expensive hardware – no membrane installation
  • Every HF cartridge is integrity tested and has an individual lot number for easy traceability

Applications

  • Clarification of mammalian/CHO cell cultures and maximizing protein recovery.
  • Cell-harvest. (Excellent results have been achieved with both E. coli whole cells and E. coli lysates, as well as other microbial process streams.)
  • Concentration and purification of vaccines.
  • Concentration and diafiltration of gene therapy products.
  • Concentration/diafiltration of monoclonal antibodies, recombinant proteins, biological macromolecules and peptides
  • As well as many other applications

Product Comparison

660x452_53872531-25-min

Green Line HF Cartridges

  • No expensive hardware
  • No membrane installation
  • Ready to use
  • No humectants
  • Reduced risk of contamination
  • Consistent, membrane performance
Steamer-660X452

Steamer Line HF Cartridges

  • Gamma irradiated
  • Ready to use
  • No pre-rinse required
  • Humectant free
  • Reduced risk of contamination
  • Consistent, membrane performance
BioProducer-660X452

ReUse HP Cartridges

  • Self-containment
  • No assembly
  • Ease of use
  • Low hold-up volume
  • High process flux
  • High yields and easy cleaning

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