Univercells Technologies NevoLine™ Upstream Platform

The Univercells Technologies NevoLine™ Upstream Platform is a flexible high-capacity, low-footprint automated platform for virus manufacturing under GMP guidelines.

  • Large-scale capacity in a compact module
  • Reliable operations for reproducible performance
  • Total Growth Area: 200 m2 OR 600 m2
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Single Automation System

With automated recipe execution from cell culture to final clarification, our NevoLine™ Upstream platform features:

    • In-line process control and monitoring
    • Single, intuitive HMI for comprehensive system operation
    • Recipe configurator to quickly start manufacturing
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Accommodates All Unit Operations

The NevoLine™ Upstream platform accommodates all unit operations from inoculation to midstream processing within a compact module. Single-use assemblies can be selected and combined to meet your process requirements.

Overview

Features and Benefits

  • Large-scale capacity in a compact module
    • Commercial-scale throughput in a 3 m² footprint
    • Integration of the intensified scale-X™ nitro bioreactor delivering high cell density
  • Total Growth Area: 200 m2 OR 600 m2
  • Reliable operations for reproducible performance
    • Process automation reducing the number of manual interventions and minimizing risk of human error
    • Seamless scalability achieved via the scale-X bioreactor structured fixed-bed design
  • Rapid manufacturing start-up
    • Ergonomic design easing installation and in-process activities
    • Continuous processing within a single automated system reducing production time
  • Ergonomic compact upstream module – A single hardware designed to fit most process specificities and ease manipulations within a controlled microenvironment
    • Plug & play platform for easy installation and operation
    • Uni-directional air flow cabinet
    • Integrated HVAC and electrical connections

Applications

  • Adenovirus
  • Lentivirus
  • AAV
  • Viral vaccine production
  • Gene therapy
  • Oncolytic viruses
  • Clinical and commercial manufacturing
  • Upstream and midstream processing of viral products

Video

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